The profiling involving substance 51 in opposition to any solar panel involving 339 kinases uncovered higher selectivity regarding CDKs, using desire regarding CDK2 as well as CDK5 over CDK9, CDK1, CDK4, and also CDK6. Compound Fifty one restricted the growth associated with Thirteen beyond 20 cancer malignancy mobile collections together with IC50 values among 0.27 and Six.Nine mu Meters, which c
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